Anycubic Kobra 2 Neo 3D Drucker 250mm/s

That guy doesn't know what he's taking about. There are no XY alignment problems out of the factory because the printer comes in two parts splitting the X and Y axis. The installation and alignment of the XZ assembly is done by the user, and thus he is the one who was supposed to align the axes.Klipper has skew correction built-in. I did no effort whatsoever to align the X/Z assembly on my N4Pro and according to the skew correction the alignment is off by 0.22 degrees. That's probably within the manufacturing tolerance of the holes/screws (meaning it would be possible to perfectly align it). That is further backed up by his claim that his replacement printer had skew in the opposite direction (unless the hole positions are really inconsistent, but I doubt that).After applying the skew correction (at the end of my start gcode, as suggested under caveats), the skew calibration print came out perfect so skew correction seems to be working.
FWIW, even before skew correction I never had issues with parts fitting even with print in place stuff. If the model is properly designed with tolerances, I doubt you're going to have any real-life issues.